Biphenyl Bromosartan
Fiosrachadh Bunaiteach:
Ainm ceimigeach: 2-cyano-4 '-bromomethyl biphenyl;
4 ′ -Bromomethyl-2-cyanobiphenyl;4-Bromomethyl-2-Cyanobiphenyl;
Àireamh CAS: 114772-54-2
Foirmle moileciuil: C14H10BrN
Cuideam moileciuil: 272.14
Àireamh EINECS: 601-327-7
Sfoirmle structarail:
Roinnean co-cheangailte: Organic intermediates;Cungaidhean-leigheis eadar-mheadhanach;Cungaidhean-leigheis stuthan amh.
Puing leaghaidh: 125-128 ° C (lit.)
Boiling point: 413.2 ± 38.0 ° C (Ro-innse)
Dùmhlachd: 1.43 ± 0.1g / cm3 (Ro-innse)
Clàr-innse ath-tharraingeach: 1.641
Puing flash: 203.7 ± 26.8 ℃
Solubility: soluble ann an uisge, soluble ann an acetonitrile no cloroform.
Feartan: Pùdar criostalach geal no geal.
Bruthadh smùide: 0.1-0.2Pa aig 20-25 ℃
| sònrachadh | aonad | àbhaisteach |
| Coltas | Pùdar criostalach geal no geal | |
| Susbaint | % | ≥99% |
| Call air tiormachadh | % | ≤1.0 |
Eadar-mheadhanan cungaidh-leigheis air an cleachdadh airson synthesis dhrogaichean antihypertensive nobhail sartan, leithid losartan, valsartan, ipsartan, ibesartan, Telmisartan, irbesartan, ester Candesartan agus drogaichean eile.
25Kg / druma, druma cairt-bhòrd;Stòradh seulaichte, stòr ann an taigh-bathair fionnar, tioram.Fuirich air falbh bho oxidants.
Seasmhach aig teòthachd an t-seòmair agus cuideam gus conaltradh le stuthan neo-fhreagarrach a sheachnadh.Bidh e ag ath-obrachadh le oxidants làidir, searbhagan, bunaitean làidir, searbhag clorides, carbon dà-ogsaid, searbhag anhydrides.
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